This chapter presents significant insights into Catholic teachings on spirituality and ethics for business, whose main reference is Jesus Christ. Catholic Social Teaching (CST) includes notions, values, principles, criteria and guidelines that support a Christian humanism for business and management. CST stresses the high dignity of each person and a vision of the business firm as a community of persons oriented to serving the common good. Human work should be central within a business firm. This leads to respect for workers' rights and to a work organization which fosters human development. Consumers' rights, stewardship of the natural environment and human ecology are also emphasized by these teachings.